There is a general consensus that labetalol is safer than other β-blockers during pregnancy, and this drug is rapidly becoming the first-line choice in conditions, such as chronic hypertension during pregnancy.
Is metoprolol safe to take during pregnancy?
Metoprolol did not cause birth defects when given to animals early in pregnancy. A study of a large number of pregnancies found that beta-blockers did not cause heart defects in babies. Does taking metoprolol cause other pregnancy complications? Metoprolol has been associated with reduced growth of the baby.
Is beta blocker contraindicated in pregnancy?
(10-14) However, beta-blockers cross the placental barrier and are associated with several adverse effects, such as delayed intrauterine growth, respiratory depression, neonatal bradycardia and hypoglycemia, particularly when treatment is started early on in the pregnancy (i.e. at 12–24 weeks).
Is propranolol safe in pregnancy?
Beta blockers may cause decreased placental perfusion, fetal and neonatal bradycardia, and hypoglycemia. Propranolol has been used safely to treat a variety of conditions during pregnancy, including hypertension and pheochromocytoma in the mother, and tachyarrhythmias in both the mother and fetus.
Is nebivolol safe in pregnancy?
The nebivolol and bisoprolol administration produce adverse effects on fetal growth and postnatal development, that limits their therapeutic use in females during pregnancy.
Can you use beta-blockers while pregnant?
Perspective: Beta-blockers are a first-line medication for hypertension during pregnancy and are also used during pregnancy for various other maternal cardiac conditions.
Can I take beta-blockers while pregnant?
“Accordingly, beta-blockers should be used in pregnancy when indicated for the treatment of various maternal medical conditions, and labetalol should be a first-line treatment choice for chronic hypertension.”
Do beta blockers cross placenta?
β-Blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women. Despite the common use of this class of medication, data that support its safety are limited. β-Blockers cross the placenta and potentially can cause physiological changes in the fetus.
What diuretic is safe in pregnancy?
The manufacturer recommends that hydrochlorothiazide should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus. The routine use of diuretics during pregnancy is not indicated or recommended.
Are Beta Blockers Safe?
These drugs also increase the chances of living longer and better with heart failure. The reviewers found that different beta blockers work better for different conditions. Safety. Beta blockers are generally safe to take.
Can propranolol cause a miscarriage?
Can taking propranolol in pregnancy cause miscarriage? A single study provided no evidence that use of propranolol in early pregnancy was linked to an increased risk of miscarriage. No further studies have assessed miscarriage rates in women taking propranolol and more research into this subject is therefore required.
Does propranolol cross the placenta?
Propranolol does not possess ISA and is categorized as a non-selective β-blocker; moreover, it readily crosses the placenta because of its lipophilicity. Therefore, propranolol might increase vascular resistance in both the mother and fetus, yielding a higher risk of FGR.
What can I take for anxiety while pregnant?
Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft).
When should I stop taking nebivolol?
Do not stop taking nebivolol without talking to your doctor. If you suddenly stop taking nebivolol it may cause angina (chest pain), heart attack, or irregular heartbeat. Your doctor will probably decrease your dose gradually over 1 to 2 weeks.
What is another name for Bystolic?
Nebivolol is a beta-blocker that is used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack. Nebivolol may also be used for purposes not listed in this medication guide.
Can I take Bystolic while pregnant?
Nebivolol Pregnancy Warnings
Use is not recommended unless clearly needed. Risk Summary: Use of beta blockers during the third trimester may increase the risk of neonatal hypotension, bradycardia, hypoglycemia, and respiratory depression.