If you are pregnant and have taken ondansetron or Zofran® during pregnancy, I want to reassure you that it likely has not affected your baby. Even if the increased risk for cleft palate or heart defects turns out to be true, the risk to your baby is still very, very small.
Is it safe to take Zofran while pregnant?
Taking Zofran while pregnant is low risk, and it has been prescribed for years for pregnancy nausea. That said, Zofran for pregnancy nausea is an off-label use, and there may be better options.
Can Zofran cause birth defects?
Summary: No evidence has been found to link the anti-nausea drug Zofran to an increased risk of birth defects. In fact, women with the condition who took Zofran reported fewer miscarriages and pregnancy terminations and higher live birth rates than women with extreme morning sickness who did not take the drug.
Is Zofran safe in the second trimester?
A new study published in the New England Journal of Medicine concluded that the popular drug Zofran (used to treat nausea, vomiting and in some cases, hyperemesis gravidarum, in early pregnancy) poses no risk to the developing fetus.
Can Zofran cause miscarriage?
Currently, no scientific evidence has linked the anti-nausea drug Zofran, frequently prescribed “off-label” for morning sickness, to an increased risk of miscarriage.
What nausea medicine is safe for pregnancy?
In fact, the FDA has approved a prescription medication for use during pregnancy that is a combination of Vitamin B6 and Unisom. It is called Diclegis. This is the only FDA approved medication for treating nausea and vomiting during pregnancy.
How quickly does Zofran work?
Zofran (ondansetron) begins to work within about 30 minutes. It reaches peak blood concentrations in about 2 hours. Zofran’s effects can last 8 to 12 hours. The Zofran dosage varies depending on the severity and cause of the nausea and vomiting.
Does Zofran cross the placenta?
2. Does Zofran Pass The Placental Barrier To A Significant Degree? Yes. We’ve already covered how Zofran is able to cross the fetal placental barrier, and was found in both human and animal fetal tissue at high concentrations.
Can you take Tylenol with Zofran while pregnant?
Interactions between your drugs
No interactions were found between Tylenol and Zofran. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
What are the side effects of Zofran?
Headache, lightheadedness, dizziness, drowsiness, tiredness, or constipation may occur. If these effects persist or worsen, notify your doctor promptly.
Can you take Zofran with prenatal vitamins?
No interactions were found between Prenatal Plus and Zofran. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
What pregnancy category is ondansetron?
US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
Is ondansetron safe during first trimester?
A new study from Brigham and Women’s Hospital finds that pregnant women taking the common anti-nausea medication ondansetron during the first trimester have no increased risk of cardiac malformations and only a slight increased risk of oral clefts.
Can Zofran cause heart defects in babies?
Now, studies have shown that one of the many birth defects associated with taking Zofran during pregnancy could be a congenital heart defect. This defect has been reported to include babies born with: Atrial Septal Defect (ASD); Ventricular Septal Defect (VSD); and.
How long does it take for Zofran to work for morning sickness?
Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. The standard tablets that are swallowed will start to work within half an hour to 2 hours. Medicines generally work faster on an empty stomach, an hour before food or 2 hours after.
Can anti nausea meds cause birth defects?
Heart defects, cleft palate and skull deformities are some of the birth defects mothers say resulted from their use of the anti-nausea drug Zofran during pregnancy. As a result, GlaxoSmithKline (GSK), the company that originally marketed the drug, has been named in more than 600 actions in federal court.